RADIOSURGERY FOR MULTIPLE BRAIN METASTASES IN NON SMALL CELL LUNG CANCER – PARADIGM SHIFT

Authors

  • Carlos André Laranja Department of External Radiotherapy, Instituto Português de Oncologia Francisco Gentil, Porto, Portugal
  • Dora Gomes Department of External Radiotherapy, Instituto Português de Oncologia Francisco Gentil, Porto, Portugal
  • Sofia Conde Department of External Radiotherapy, Instituto Português de Oncologia Francisco Gentil, Porto, Portugal
  • Artur Aguiar Department of External Radiotherapy, Instituto Português de Oncologia Francisco Gentil, Porto, Portugal
  • Luísa Rolim Department of Radiotherapy, Instituto Português de Oncologia Francisco Gentil, Coimbra, Portugal
  • Luísa Carvalho Department of External Radiotherapy, Instituto Português de Oncologia Francisco Gentil, Porto, Portugal
  • Andreia Pires Department of External Radiotherapy, Instituto Português de Oncologia Francisco Gentil, Porto, Portugal

DOI:

https://doi.org/10.47724/MIRTJ.2021.i01.a002

Keywords:

Stereotactic, Radiotherapy, Radiosurgery, Brain metastases

Abstract

Non-small cell lung cancer (NSCLC) is a disease with a poor prognosis. The five-year overall survival rate for metastatic disease is 6.1%. Brain metastases (BM) are common complications during the course of NSCLC progression and represent a major cause of morbidity and mortality. In recent years, stereotactic radiosurgery (SRS) has become an attractive non-invasive treatment option for patients with BM. Although SRS is not the standard treatment for patients with more than four BM, several published studies have demonstrated promising results. This clinical case report presents a patient with NSCLC diagnosed with nine BM who was treated with SRS. During follow-up, all brain lesions showed complete response with minimal impact on the patient’s quality of life.

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Published

01.12.2021
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